Studies on Lymphocytes. I. Lymphopenia Produced by Prolonged Extracorporeal Irradiation of Circulating Blood
نویسندگان
چکیده
منابع مشابه
Studies on lymphocytes. I. Lymphopenia produced by prolonged extracorporeal irradiation of circulating blood.
T HERE ARE numerous conflicting concepts in respect to the function, fate and life span of lymphocytes.15 Radiation of segments of the wholebody or of lymphocytes in vitro has long been exploited in the study of lymphocytes.69 However, irradiation of the whole-body or segments injures lymphopoietic tissue and the in vitro environment separates the lymphocyte from homeostatic influences. We reas...
متن کاملEffects of Gamma Irradiation on Proliferation and IL-5 Production of Peripheral Blood Lymphocytes
Gamma irradiation is routinely used for suppression of lymphocyte function in transfusion and transplantation procedures. In recent years, some investigators focused on the effects of ionizing radiation on special aspects of lymphocyte function and considered the possibility of its clinical application for treatment of some immunological disorders. In this study, we evaluated the effects of fiv...
متن کاملExtracorporeal Irradiation of Blood (ECIB) in Man
LL PRESENT FORMS OF THERAPY for acute myelocytic leukemia (AML) injure or destroy normal as well as leukemic cells. The action of anti-metabolic chemotherapeutic drugs is largely directed at disrupting flucleic acid synthesis and, thus, replication of cells. The alkylating agents and whole body radiation are effective in reducing cell production by slowing the generative cycle and directly kill...
متن کاملStudies on blood viscosity during extracorporeal circulation.
Blood viscosity was studied during extracorporeal circulation by means of a cone in cone viscometer. This rotational viscometer provides sixteen kinds of shear rate, ranging from 0.05 to 250.2 sec-1 • Merits and demerits of the equipment were described comparing with the capillary viscometer. In experimental study it was well demonstrated that the whole blood viscosity showed the shear rate dep...
متن کاملThe effects of prolonged azathioprine administration on blood cells, lymphocytes and immunoglobulins of Iranian mixed-breed dogs
Background: Azathioprine is an immunosuppressive agent that is used in a variety of dermatologic, digestive and hematologic disorders in both humans and small animals. Aims: The effects of long term Azathioprine administration on complete blood count, rate of CD4+ and CD8+ lymphocytes, serum immunoglobulins and protein concentrations of mixed-breed dogs were evaluated in this study. Methods: 24...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Blood
سال: 1962
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v20.2.203.203